May 18, 2025
EP. 342 — Sarah Silverman Returns Again
Comedian and actress Sarah Silverman feels rejoice/dead inside about being Conan O’Brien’s friend.
Sarah sits down with Conan once more for an in-depth discussion on human anatomy, adapting her memoir into a musical, and grieving her parents through her new comedy special PostMortem. Later, Conan, Matt, and Sona unearth the origins of their names as they Review the Reviewers.
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EP. 348 — Diego Luna
Guest Diego Luna
Actor Diego Luna feels really comfortable about being Conan O’Brien’s friend.
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Talent coordinator Maddie Ogden returns for a follow-up delivery of alternative snacks, and Conan’s team helps him decide on the right food product to stand behind.
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EP. 347 — David Spade Returns
Guest David Spade
Comedian and actor David Spade feels somewhat sick about being Conan O’Brien’s friend.